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Engineering aluminum hydroxyphosphate nanoparticles with well-controlled surface property to enhance humoral immune responses as vaccine adjuvants
Aluminum hydroxyphosphate Vaccine adjuvants Staphylococcus aureus
2023/6/21
Engineering aluminum hydroxyphosphate nanoparticles with well-controlled surface property to enhance humoral immune responses as vaccine adjuvants。
Protein controlled by both light and temperature can inform cell signal pathways（图）
蛋白质 细胞 信号通路
2023/7/12
Most organisms have proteins that react to light. Even creatures that don’t have eyes or other visual organs use these proteins to regulate many cellular processes, such as transcription, translation,...
Trevor Franklin, a doctoral student in Cornell’s Robert Frederick Smith School of Chemical and Biomolecular Engineering, was preparing a study about anti-fouling surfaces when he noticed something str...
The movement of small water droplets is controlled by means of a magnet
magnet water movement magnetic field
2021/8/11
A new study has presented and characterized the formation and properties of a superparamagnetic ring, which fits snugly around a drop of water due to liquid-liquid interaction, and allows the drops to...
Mysterious Majorana quasiparticle is now closer to being controlled for quantum computing（图）
Majorana quasiparticle controlled quantum computing
2019/10/23
The fame of the Majorana particle stems from its strange properties -- it is the only particle that is its own antiparticle -- and from its potential to be harnessed for future quantum computing.In re...
The effects of dietary protein intake on appendicular lean mass and muscle function in elderly men: a 10-wk randomized controlled trial
nutrient requirements dietary protein skeletal muscle older adults whole foods
2018/11/21
Background: The Recommended Daily Allowance (RDA) for protein intake in the adult population is widely promoted as 0.8 g · kg−1 · d−1. Aging may increase protein requirements, particularly...
Bone mineral density during pregnancy in women participating in a randomized controlled trial of vitamin D supplementation
bone mineral content bone mineral density cholecalciferol pregnancy vitamin D
2018/11/21
Background: Little is known about bone mineral density (BMD) during pregnancy. Advances in technology with lower radiation emissions by dual-energy X-ray absorptiometry instruments now permit the safe...
Randomized controlled trial on the impact of early-life intervention with bifidobacteria on the healthy infant fecal microbiota and metabolome
infant gut microbiota probiotics bifidobacteria breastfeeding 16S rRNA gene metabolomics
2018/11/20
Background: Early-life colonization of the intestinal tract is a dynamic process influenced by numerous factors. The impact of probiotic-supplemented infant formula on the composition and function of ...
Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial
stroke potassium magnesium enriched salt neurologic performance
2018/11/20
Background: Stroke is one of the leading causes of mortality and neurologic deficits. Management measures to improve neurologic outcomes are in great need. Our previous intervention trial in elderly s...
Taurolidine-citrate-heparin lock reduces catheter-related bloodstream infections in intestinal failure patients dependent on home parenteral support: a randomized, placebo-controlled trial
antimicrobial catheter lock bacteremia catheter infections
2018/11/19
Background: In patients with intestinal failure who are receiving home parenteral support (HPS), catheter-related bloodstream infections (CRBSIs) inflict health impairment and high costs.
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial
isoflavone bone turnover bioavailability probiotics osteopenia postmenopause equol bone density
2018/11/19
Background: Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement therapy. However, hormone replacement therap...
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial
isoflavone bone turnover bioavailability probiotics osteopenia postmenopause equol bone density
2018/11/16
Background: Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement therapy. However, hormone replacement therap...
The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
2018/11/16
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
Very-long-chain ω-3 fatty acid supplements and adipose tissue functions: a randomized controlled trial
EPA DHA macrophage lipolysis inflammation insulin resistance
2018/11/14
Background: Increased omega-3 (n–3) fatty acid consumption is reported to benefit patients with metabolic syndrome, possibly due to improved adipose tissue function.
Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue: a randomized controlled trial
DNA methylation epigenetics EWAS Illumina 450k methylation array LIPOGAIN cohort obesity overfeeding polyunsaturated fat prediction saturated fat
2018/11/13
Background: Dietary fat composition can affect ectopic lipid accumulation and, thereby, insulin resistance. Diets that are high in saturated fatty acids (SFAs) or polyunsaturated fatty acids (PUFAs) h...