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近日，Theranostics杂志（IF=8.854）在线发表了我校生命学院2012级博士生韩洋洋和青年教师黄伟伟论文“Triptolide Inhibits the AR Signaling Pathway to Suppress the Proliferation of Enzalutamide Resistant Prostate Cancer Cells”（DOI:10.7150/thno...
Triptolide Directly Inhibits dCTP Pyrophosphatase
Pyrophosphatase Triptolide Directly Inhibits
2014/11/25
Triptolide is a potent natural product, with documented antiproliferative, immunosuppressive, anti-inflammatory, antifertility, and antipolycystic kidney disease effects. Despite a wealth of knowledge...
The antifertility effect of triptolide and other related compounds, isolated from Tripterygium wilfordii, has been demonstrated in male rats. The exact sites and mechanism of action of triptolide ...
Long-term effects of triptolide on spermatogenesis, epididymal sperm function, and fertility in male rats
spermatogenesis epididymal sperm function fertility male rats
2008/12/25
Prior studies had suggested that triptolide, a diterpene triepoxide isolated from a Chinese medicinal plant, might be an attractive candidate as a post-testicular male contraceptive agent. Despite the...
Posttesticular antifertility action of triptolide in the male rat: evidence for severe impairment of cauda epididymal sperm ultrastructure
Posttesticular antifertility action triptolide male rat sperm ultrastructure
2008/12/25
A variety of active diterpene epoxides, including the triptolide (isolated from Tripterygium wilfordii) have been reported to cause infertility in male rats. Previously, we showed that oral admini...