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Treating cancer with combinations of drugs can be more effective than using a single drug. However, figuring out the optimal combination of drugs, and making sure that all of the drugs reach the right...
Tumor-targeting system uses cancer’s own mechanisms to betray its location
Tumor-targeting system cancer’s own mechanisms betray its location
2017/3/13
By hijacking a cancer cell’s own metabolism, researchers have found a way to tag and target elusive cancers with small-molecule sugars. This opens treatment pathways for cancers that are not responsiv...
Emerging strategies for therapeutic targeting of the tumour microenvironment
Emerging strategies tumour microenvironment
2015/4/14
Metastatic cancers are often resistant to conventional chemotherapy and radiotherapy, reflecting an unmet need for novel therapeutic approaches to inhibit metastasis. Growing evidence highlights the i...
Targeting treatment for colorectal cancer: the EGFR antibody story
Targeting treatment colorectal cancer
2015/4/13
Frequent overexpression of the epidermal growth factor receptor in colorectal cancer was the rationale for the development of anti-epidermal growth factor receptor antibodies. The development of the d...
WEST LAFAYETTE, Ind. – Researchers have developed a chip capable of simulating a tumor's "microenvironment" and plan to use the new system to test the effectiveness of nanoparticles and drugs that tar...
Understanding of the particular cancer cells within a tumour that drive its growth could now advance more rapidly, thanks to Oxford University scientists.
They show in the journal PNAS how a crucial...
Current status of tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) targeting cancer therapy
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) TRAIL receptor 1 (TRAIL-R1), TRAIL receptor 2 (TRAIL-R2) apoptosis KM mouseTM monoclonal antibody targeting therapeutics
2009/7/15
Monoclonal antibodies have already established a secure position as a very promising strategy for anti-tumor therapeutics. High specificity and high affinity are attractive characteristics of antibodi...
Hyperthermic sensitizers targeting heat-induced signal transductions
hyperthermic sensitivity heat apoptosis inhibitor sensitizer
2009/7/15
Hyperthermia has been used as one of the efficacious cancer therapies. To develop more efficient regimens for various malignant tumors, the attention has focused on searching for substances to sensiti...
期刊信息
篇名
Inhibition of endothelial cell proliferation by targeting Rac1 GTPase with small interference RNA in tumor cells.
语种
英文
撰写或编译
撰写
作者
薛妍,毕锋,张学庸,潘阳林,刘娜,郑毅,樊代明
第一作者单位
第四军医大学西京医院消化病研究所
刊物名称
Biochem...
Targeting Cancer Stem Cells to Stop Brain Tumors（图）
Cancer Stem Cell Brain Tumors James S. McDonnell Foundation
2006/11/13
October 30, 2006， Research on a novel approach to brain cancer – exploring the notion that the source of a brain tumor is a normal stem cell that has gone bad – is moving forward thanks to an award fr...