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We previously showed that mortality from infectious diseases among young adults in rural Gambia is strongly correlated with the season of their birth. This suggests that early life insults that inv...
Designing studies to examine the role of nutrition in disease prevention can provide interesting challenges. For example, assessing the effect of nutritional interventions on immune function is oft...
It has been suggested that vitamin E can counteract the age-associated decline in cellular immune responsiveness (CIR). Particularly, T helper cell type 1 (Th1) activity, ie, interferon (IFN) g–pro...
Background: Low birth weight is generally an outcome of a fetal insult or nutritional insufficiency. Recent studies have shown that such exposure early in life may have long-term implications for late...
Supplementation of nutritional deficiencies helps to improve immune function and resistance to infections in malnourished subjects. However, the suggested benefits of dietary supplementation for immun...
Greatly increasing dietary flaxseed oil [rich in the n−3 polyunsaturated fatty acid (PUFA) α-linolenic acid (ALA)] or fish oil [rich in the long-chain n−3 PUFAs eicosapentaenoic (EPA) and ...
Background: Natural killer (NK) cells play a role in natural immunity against tumor and infected cells. Advanced aging is associated with functional impairment of NK cells and increased susceptibil...

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