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北京大学王嘉东课题组Molecular Cell发文揭示放射损伤修复调控新机制(图)
北京大学 王嘉东 课题组 Molecular Cell 发文 揭示 放射 损伤修复 调控 新机制
2019/7/30
染色体的完整性和遗传信息的精准传递对于细胞以及个体而言至关重要,而放射损伤所导致的DNA双链断裂会直接导致染色体的断裂、丢失和重排,如不能及时修复则会导致细胞的死亡或者癌变。MRN(MRE11/RAD50/NBS1)复合体在放射损伤修复通路中扮演着重要的角色,该复合体作为DNA损伤的“感应器”最先识别DNA双链断裂的位点:一方面,MRN可以引起ATM磷酸化级联反应,激活细胞周期检验点;另一方面,M...
Assessing accuracy of gas-driven permeability measurements: a comparative study of diverse Hassler-cell and probe permeameter devices
gas-driven permeability measurements diverse Hassler-cell probe permeameter devices
2015/1/6
Permeability is one of the most important petrophysical parameters to describe the reservoir properties of sedimentary rocks, pertaining to problems in hydrology, geothermics, and hydrocarbon reservoi...
Potentiometric open-cell titration for seawater alkalinity considering temperature dependence of titrant density and Nernst response of pH electrode
Balkalinity open-cell titration potentiometric method HCl density Nernst response
2017/4/11
The total alkalinity (AT) of seawater is one of the parameters required to characterize carbonate systems, which are
essential for studying the greenhouse effects of carbon dioxide (CO2) on the Earth...
Particle‐in‐cell simulation of incoherent scatter radar spectral distortions related to beam‐plasma interactions in the auroral ionosphere
incoherent scatter radar auroral ionosphere
2017/3/22
An electrostatic parallel particle‐in‐cell (EPPIC) code that allows for particle beam
injections and multiple boundary conditions is used to investigate the beam‐plasma
interaction and its manifesta...