搜索结果: 1-15 共查到“生物化学 Role”相关记录16条 . 查询时间(0.078 秒)
A role for leukocyte integrins and extracellular matrix remodeling of adipose tissue in the risk of weight regain after weight loss
healthy overweight/obese participants human dietary intervention weight regain after weight loss adipose tissue microarray extracellular matrix and inflammation
2018/11/13
Background: Weight loss (WL) is often followed by weight regain after an energy-restricted dietary intervention (DI). When people are following a diet, the volume of an adipocyte decreases by loss of ...
The role of gluten consumption at an early age in celiac disease development: a further analysis of the prospective PreventCD cohort study
celiac disease children gluten HLA European cohort
2018/11/13
Background: We previously found that the introduction of small quantities of gluten at 4–6 mo of age did not reduce the risk of celiac disease (CD) in a group of high-risk children. However, the consu...
Old enzyme,new role
Old enzyme new role
2017/2/16
A team of researchers at the University of Delaware has discovered a new function for an enzyme that has long been known to have a central role in bacterial metabolism.Maciek Antoniewicz, Centennial J...
A Test of the Role of Electrostatic Interactions in Determining the CO Stretch Frequency in Carbonmonoxymyoglobin
Electrochemistry Escherichia coli Humans Mutagenesis, Site-Directed Myoglobin Point Mutation Protein Conformation Recombinant Proteins Spectroscopy, Fourier Transform Infrared Vibration
2016/5/23
The vibrational frequency of CO bound to myoglobin can be varied by up to 60 cm-1 by making site-specific mutations in the distal pocket. These changes may result from specific chemical interactions b...
The role of N -linked glycans in protein quality control in the early secretory pathway
ER quality protein abnormal protein protein degradation the cavity cytosol proteasome chitosan tyrosine
2014/12/11
The ER quality control machinery maintains the fidelity of the protein maturation process by sorting aberrant proteins for ER-associated protein degradation (ERAD), a process requiring retranslocation...
The role of the crumbs complex in vertebrate rod morphogenesis and its regulation by a novel FERM protein mosaic eyes
Zebrafish Mosaic eyes retinal texture protein complex crumbs protein cell polarity
2014/12/11
Mutations in zebrafish mosaic eyes result in the disrupted retina lamination and other abnormalities. The moe locus encodes a FERM protein. In this study I sought to determine in which molecular pathw...
TRAF-interacting protein, an inhibitor of the canonical nuclear factor-kappaB pathway, plays a key role in the estradiol -dependent apoptosis of the dual-phenotype gamma amino butyric acid/glutamate neurons in the anteroventral periventricular nucleus of the male rat
Mediated estradiol LH surge neurons male AVPV E2 - mediated cell death neurons
2014/12/11
The anteroventral periventricular nucleus (AVPV) of the preoptic area mediates the positive feedback effects of estradiol (E2) on LH surge in rats. Consistent with their role in female reproduction, t...
The role of the ER glucosyltransferase in the quality control of glycoprotein maturation
Pure sciences Biological sciences Endoplasmic reticulum Glycoprotein Glycoprotein glucosyltransferase 1 Protein folding Protein maturation Glucosyltransferase
2014/12/11
N-linked glycans serve as quality control tags in the eukaryotic secretory pathway. The endoplasmic reticulum (ER) protein UDP-glucose: glycoprotein glucosyltransferase 1 (GT1) is the main enzyme that...
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome
Ribosomes the extension of cyclic code metastable state catalytic interactive translocation protein
2014/12/11
Translocation is the process by which the ribosome advances the mRNA:tRNA complex by a one-codon step during the elongation cycle of translation. In the pre-translocation state, the ribosome transitio...
The Role Of Edem1 In The Quality Control And Degradation Of Misfolded Glycoproteins
Biological sciences Degradation Glycoproteins Misfolded Protein misfolding
2014/12/10
Immature or incompletely assembled proteins that do not fold correctly are retained in the endoplasmic reticulum (ER) by quality control factors. Terminally misfolded glycoproteins are eventually sort...
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome
Biological sciences Hybrid state L1 Ribosome rRNA Translocation
2014/12/10
Translocation is the process by which the ribosome advances the mRNA:tRNA complex by a one-codon step during the elongation cycle of translation. In the pretranslocation state, the ribosome transition...
NOVEL STRATEGIES TO MODULATE SYNAPTIC COMMUNICATION AND INVESTIGATE THE ROLE OF HDAC6 IN ALZHEIMER’S DISEASE
Photochemistry GABA_A receptors Alzheimer's disease Tau HDAC6
2014/12/10
Neuronal communication is mediated by chemical signaling at the synapse. The underlying molecular mechanisms of learning and memory are poorly understood. Very few tools are available to study how mem...
Characterization of the norepinephrine-activation of adenylate cyclase suggests a role in memory affirmation pathways. Overexposure to epinephrine inactivates adenylate-cyclase,a causal pathway for stress-pathologies
the norepinephrine-activation adenylate cyclase suggests
2011/1/5
Incubation with noradrenaline (norepinephrine) of isolated membranes of rat's brain corpus striatum and cortex, showed that ionic-magnesium (Mg2+) is required for the neurotransmitter activatory respo...
期刊信息
篇名
The role of tryptophan residues in E.coli arginyl-tRNA synthetase
语种
英文
撰写或编译
撰写
作者
Qing-Shuo Zhang,En-Duo Wang,Ying-Lai Wang
第一作者单位
State Key Laboratory, Shanghai Institute of Biochemistry, T...
期刊信息
篇名
Enhancement of J6-1 human leukemic cell proliferation by membrane-bound M-SCF througf a cell-cell contact mechanism ll.Role of an M-CSF receptor-like membrane protein
语种
英文
撰写或编译
作者
Wu KF,Rao ...