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Genetic studies link indigenous peoples in the Amazon and Australasia
Genetic studies link indigenous peoples Amazon Australasia
2015/8/4
Native Americans living in the Amazon bear an unexpected genetic connection to indigenous people in Australasia, suggesting a previously unknown wave of migration to the Americas thousands of years ag...
The Biological Effects of Psychotherapy in Major Depressive Disorders: A Review of Neuroimaging Studies
Depression Psychotherapy Cognitive Behavior Psychotherapy Interpersonal Psychotherapy Psychodynamic Psychotherapy Neurobiology
2013/2/20
Major depressive disorder (MDD) is a syndrome, which is quite frequent in the society, can be recurrent and shows symptoms of emotional, cognitive and behavioral disorder. Brain imaging studies suppor...
Population Structure and Cryptic Relatedness in Genetic Association Studies
Population Structure Cryptic Relatedness Genetic Association Studies
2010/11/16
We review the problem of confounding in genetic association studies, which arises principally because of population structure and cryptic relatedness. Many treatments of the problem consider only a si...
山东临朐人群HLA等位基因多态性与幽门螺杆菌感染关系的研究Studies of the Relationship of HLA Polymorphisms and the Infection of H.pylori in the Population of Linqu in Shandong Province
人类白细胞抗原（HLA） PCR SSP 幽门螺杆菌 遗传易感性
2008/1/10
摘要为了研究山东临朐地区健康人白细胞抗原（HLA）Ⅰ类等位基因多态性与幽门螺杆菌（Hp）感染的关系，运用序列特异性引物聚合酶链反应（PCRSSP）的方法，检测Hp阳性人群（90例）和Hp阴性人群（49例）的HLAⅠ类和Ⅱ类等位基因。结果在HLAⅠ类（A、B、CW）的共68个等位基因多态中，发现在感染及非感染人群中存在4个显著性差异的位点；在HLAⅡ类（DRB1、DQB1和DRB3、DRB4...
摘要再生基因家族自1988年被发现以来，其在糖尿病、炎症创伤与肿瘤尤其在消化系统肿瘤中的作用日渐被重视。越来越多的该家族成员被发现，并已开始考虑在临床治疗中应用。这些研究开始显示再生基因家族的潜在应用价值。
Abstract:Since the first member of Reg gene was discovered in 1988,it has been verified that Re...
人类单纯性先天性心脏病中TBX5基因的突变及表达研究 Studies on the Mutation and Expression of TBX5 Gene in Human Simple Congenital Heart Disease
TBX5基因 心脏发育 突变 表达
2007/12/31
摘要应用PCR-DGGE方法在61个单纯性先天性心脏病核心家系共216位成员中检测TBX5基因8个外显子的突变情况；以β-actin作为内对照对单纯性先天性心脏病患者（房间隔缺损12例、室间隔缺损16例、法洛四联症6例）和3个非先天性心脏病患者（正常对照）心肌标本进行RT-PCR扩增和定量分析，观察TBX5基因在mRNA水平有无差异。研究了人类单纯性先天性心脏病患者中TBX5基因突变及表达情况。在...